Publications of Juan Pablo Lopez

Sen, P.; Ortiz, O.; Brivio, E.; Menegaz, D.; Sotillos Elliott, L.; Du, Y.; Ries, C.; Chen, A.; Wurst, W.; Lopez, J. P. et al.; Eder, M.; Deussing, J. M.: A bipolar disorder-associated missense variant alters adenylyl cyclase 2 activity and promotes mania-like behavior. MOLECULAR PSYCHIATRY 30 (1), pp. 97 - 110 (2025)

Brivio, E.; Kos, A.; Ulivi, A. F.; Karamihalev, S.; Reßle, A.; Stoffel, R.; Hirsch, D.; Stelzer, G.; Schmidt, M. V.; Lopez, J. P. et al.; Chen, A.: Sex shapes cell-type-specific transcriptional signatures of stress exposure in the mouse hypothalamus. CELL REPORTS 42 (8), 112874 (2023)

Kos, A.; Lopez, J. P.; Bordes, J.; De Donno, C.; Dine, J.; Brivio, E.; Karamihalev, S.; Luecken, M. D.; de Almeida-Correa, S.; Gasperoni, S. et al.; Dick, A.; Miranda, L.; Buettner, M.; Stoffel, R.; Flachskamm, C.; Theis, F. J.; Schmidt, M. V.; Chen, A.: Early life adversity shapes social subordination and cell type-specific transcriptomic patterning in the ventral hippocampus. SCIENCE ADVANCES 9 (48), eadj3793 (2023)

Lin, R.; Kos, A.; Lopez, J. P.; Dine, J.; Fiori, L. M.; Yang, J.; Ben-Efraim, Y. J.; Aouabed, Z.; Ibrahim, P.; Mitsuhashi, H. et al.; Wong, T. P.; Ibrahim, E. C.; Belzung, C.; Blier, P.; Farzan, F.; Frey, B. N.; Lam, R. W.; Milev, R.; Muller, D. J.; Parikh, S. V.; Soares, C.; Uher, R.; Nagy, C.; Mechawar, N.; Foster, J. A.; Kennedy, S. H.; Chen, A.; Turecki, G.: SNORD90 induces glutamatergic signaling following treatment with monoaminergic antidepressants. ELIFE 12, e85316 (2023)

van Doeselaar, L.; Stark, T.; Mitra, S.; Yang, H.; Bordes, J.; Stolwijk, L.; Engelhardt, C.; Kovarova, V.; Narayan, S.; Brix, L. M. et al.; Springer, M.; Deussing, J. M.; Lopez, J. P.; Czisch, M.; Schmidt, M. V.: Sex-specific and opposed effects of FKBP51 in glutamatergic and GABAergic neurons: Implications for stress susceptibility and resilience. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 120 (23), e2300722120 (2023)

Lopez, J. P.; Luecken, M. D.; Brivio, E.; Karamihalev, S.; Kos, A.; De Donno, C.; Benjamin, A.; Yang, H.; Dick, A. L. W.; Stoffel, R. et al.; Flachskamm, C.; Ressle, A.; Roeh, S.; Huettl, R. E.; Parl, A.; Eggert, C.; Novak, B.; Yan, Y.; Yeoh, K.; Lebar, M.; Hauger, B.; Harbich, D.; Schmid, B.; Di Giaimo, R.; Turck, C. W.; Schmidt, M. V.; Deussing, J. M.; Eder, M.; Dine, J.; Theis, F. J.; Chen, A.: Ketamine exerts its sustained antidepressant effects via cell-type-specific regulation of Kcnq2. NEURON 110 (14), pp. 2283 - 2298.e9 (2022)

Hausl, A. S.; Brix, L.; Hartmann, J.; Poehlmann, M. L.; Lopez, J. P.; Menegaz, D.; Brivio, E.; Engelhardt, C.; Roeh, S.; Bajaj, T. et al.; Rudolph, L.; Stoffel, R.; Hafner, K.; Goss, H. M.; Reul, J. M. H. M.; Deussing, J. M.; Eder, M.; Ressler, K. J.; Gassen, N. C.; Chen, A.; Schmidt, M. V.: The co-chaperone Fkbp5 shapes the acute stress response in the paraventricular nucleus of the hypothalamus of male mice. MOLECULAR PSYCHIATRY (2021)

Lin, R.; Lopez, J. P.; Cruceanu, C.; Pierotti, C.; Fiori, L. M.; Squassina, A.; Chillotti, C.; Dieterich, C.; Mellios, N.; Turecki, G.: Circular RNA circCCNT2 is upregulated in the anterior cingulate cortex of individuals with bipolar disorder. TRANSLATIONAL PSYCHIATRY 11 (1), 629 (2021)

Lopez, J. P.; Brivio, E.; Santambrogio, A.; De Donno, C.; Kos, A.; Peters, M.; Rost, N.; Czamara, D.; Brueckl, T.; Roeh, S. et al.; Poehlmann, M. L.; Engelhardt, C.; Ressle, A.; Stoffel, R.; Tontsch, A.; Villamizar, J. M.; Reincke, M.; Riester, A.; Sbiera, S.; Fassnacht, M.; Mayberg, H. S.; Craighead, W. E.; Dunlop, B. W.; Nemeroff, C. B.; Schmidt, M. V.; Binder, E. B.; Theis, F. J.; Beuschlein, F.; Andoniadou, C. L.; Chen, A.: Single-cell molecular profiling of all three components of the HPA axis reveals adrenal ABCB1 as a regulator of stress adaptation. SCIENCE ADVANCES 7 (5), eabe4497 (2021)

Schraut, K.-G.; Kalnytska, O.; Lamp, D.; Jastroch, M.; Eder, M.; Hausch, F.; Gassen, N. C.; Moore, S.; Nagaraj, N.; Lopez, J. P. et al.; Chen, A.; Schmidt, M. V.: Loss of the psychiatric risk factor SLC6A15 is associated with increased metabolic functions in primary hippocampal neurons. EUROPEAN JOURNAL OF NEUROSCIENCE 53 (2), pp. 390 - 401 (2021)

Brivio, E.; Lopez, J. P.; Chen, A.: Sex differences: Transcriptional signatures of stress exposure in male and female brains. GENES BRAIN AND BEHAVIOR 19 (3), e12643 (2020)

Fiori, L. M.; Kos, A.; Lin, R.; Theroux, J.-F.; Lopez, J. P.; Kühne, C.; Eggert, C.; Holzapfel, M.; Huettl, R. E.; Mechawar, N. et al.; Belzung, C.; Ibrahim, E. C.; Chen, A.; Turecki, G.: miR-323a regulates ERBB4 and is involved in depression. MOLECULAR PSYCHIATRY (2020)

Lin, R.; Kos, A.; Dine, J.; Fiori, L.; Ben-Efraim, Y.; Lopez, J. P.; Theroux, J.-F.; Aouabed, Z.; Ibrahim, P.; Wong, T. P. et al.; Ibrahim, E. C.; Chen, A.; Turecki, G.: Role of small nucleolar RNAs in antidepressant treatment. In JOURNAL OF PSYCHIATRY & NEUROSCIENCE, 47 (3), pp. S15 - S16. (2022)