Publications of Silvia Martinelli

Hartmann, J.; Bajaj, T.; Otten, J.; Klengel, C.; Ebert, T.; Gellner, A.-K.; Junglas, E.; Hafner, K.; Anderzhanova, E. A.; Tang, F. et al.; Missig, G.; Rexrode, L.; Trussell, D. T.; Li, K. X.; Pohlmann, M. L.; Mackert, S.; Geiger, T. M.; Heinz, D. E.; Lardenoije, R.; Dedic, N.; McCullough, K. M.; Prochnicki, T.; Rhomberg, T.; Martinelli, S.; Payton, A.; Robinson, A. C.; Stein, V.; Latz, E.; Carlezon Jr., W. A.; Hausch, F.; Schmidt, M. V.; Murgatroyd, C.; Berretta, S.; Klengel, T.; Pantazopoulos, H.; Ressler, K. J.; Gassen, N. C.: SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration. NATURE COMMUNICATIONS 15 (1), 2635 (2024)

Martinelli, S.; Hafner, K.; Ködel, M.; Knauer-Arloth, J.; Gassen, N. C.; Binder, E. B.: Differential Dynamics and Roles of FKBP51 Isoforms and Their Implications for Targeted Therapies. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 25 (22), 12318 (2024)

Stepan, J.; Heinz, D. E.; Dethloff, F.; Wiechmann , S.; Martinelli, S.; Hafner, K.; Ebert, T.; Junglas, E.; Haeusl, A. S.; Poehlmann, M. L. et al.; Jakovcevski, M.; Pape, J. C.; Zannas, A. S.; Bajaj , T.; Hermann, A.; Ma, X.; Pavenstaedt, H.; Schmidt, M. V.; Philipsen, A.; Turck, C. W.; Deussing, J. M.; Rammes, G.; Robinson, A. C.; Payton, A.; Wehr, M. C.; Stein, V.; Murgatroyd, C.; Kremerskothen, J.; Kuster, B.; Wotjak, C. T.; Gassen, N. C.: Inhibiting Hippo pathway kinases releases WWC1 to promote AMPAR-dependent synaptic plasticity and long-term memory in mice. SCIENCE SIGNALING 17 (834), eadj6603 (2024)

Matosin, N.; Arloth, J.; Czamara, D.; Edmond, K. Z.; Maitra, M.; Froehlich, A. S.; Martinelli, S.; Kaul, D.; Bartlett, R.; Curry, A. R. et al.; Gassen, N. C.; Hafner, K.; Mueller, N. S.; Worf, K.; Rehawi, G.; Nagy, C.; Halldorsdottir, T.; Cruceanu, C.; Gagliardi, M.; Gerstner, N.; Ködel, M.; Murek, V.; Ziller, M. J.; Scarr, E.; Tao, R.; Jaffe, A. E.; Arzberger, T.; Falkai, P.; Kleinmann, J. E.; Weinberger, D. R.; Mechawar, N.; Schmitt, A.; Dean, B.; Turecki, G.; Hyde, T. M.; Binder, E. B.: Associations of psychiatric disease and ageing with FKBP5 expression converge on superficial layer neurons of the neocortex. ACTA NEUROPATHOLOGICA 145 (4), pp. 439 - 459 (2023)

Cruceanu, C.; Dony, L.; Krontira, A. C.; Fischer, D. S.; Roeh, S.; Di Giaimo, R.; Kyrousi, C.; Kaspar, L.; Arloth, J.; Czamara, D. et al.; Gerstner, N.; Martinelli, S.; Wehner, S.; Breen, M. S.; Koedel, M.; Sauer, S.; Sportelli, V.; Rex-Haffner, M.; Cappello, S.; Theis, F. J.; Binder, E. B.: Cell-Type-Specific Impact of Glucocorticoid Receptor Activation on the Developing Brain: A Cerebral Organoid Study. AMERICAN JOURNAL OF PSYCHIATRY 179 (5), pp. 375 - 387 (2022)

Stepan, J.; Heinz, D. E.; Dethloff, F.; Bajaj, T.; Zellner, A.; Hafner, K.; Wiechmann, S.; Mackert, S.; Mecdad, Y.; Rabenstein, M. et al.; Ebert, T.; Martinelli, S.; Haeusl, A. S.; Poehlmann, M. L.; Hermann, A.; Ma, X.; Pavenstaedt, H.; Schmidt, M. V.; Philipsen, A.; Turck, C. W.; Deussing, J. M.; Kuster, B.; Wehr, M. C.; Stein, V.; Kremerskothen, J.; Wotjak, C. T.; Gassen, N. C.: Hippo-released WWC1 facilitates AMPA receptor regulatory complexes for hippocampal learning. CELL REPORTS 41 (10), 111766 (2022)

Martinelli, S.; Anderzhanova, E.; Bajaj, T.; Wiechmann, S.; Dethloff, F.; Weckmann, K.; Heinz, D. E.; Ebert, T.; Hartmann, J.; Geiger, T. M. et al.; Doengi, M.; Hafner, K.; Poehlmann, M. L.; Jollans, L.; Philipsen, A.; Schmidt, S. V.; Schmidt, U.; Maccarrone, G.; Stein, V.; Hausch, F.; Turck, C. W.; Schmidt, M. V.; Gellner, A.-K.; Kuster, B.; Gassen, N. C.: Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion. NATURE COMMUNICATIONS 12 (1), 4643 (2021)

Gassen, N. C.; Niemeyer, D.; Muth, D.; Corman, V. M.; Martinelli, S.; Gassen, A.; Hafner, K.; Papies, J.; Moesbauer, K.; Zellner, A. et al.; Zannas, A. S.; Herrmann, A.; Holsboer, F.; Brack-Werner, R.; Boshart, M.; Mueller-Myhsok, B.; Drosten, C.; Mueller, M. A.; Rein, T.: SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection. NATURE COMMUNICATIONS 10, 5770 (2019)

Zannas, A. S.; Jia, M.; Hafner, K.; Baumert, J.; Wiechmann, T.; Pape, J. C.; Arloth, J.; Koedel, M.; Martinelli, S.; Roitman, M. et al.; Roeh, S.; Haehle, A.; Emeny, R. T.; Iurato, S.; Carrillo-Roa, T.; Lahti, J.; Raikkonen, K.; Eriksson, J. G.; Drake, A. J.; Waldenberger, M.; Wahl, S.; Kunze, S.; Lucae, S.; Bradley, B.; Gieger, C.; Hausch, F.; Smith, A. K.; Ressler, K. J.; Mueller-Myhsok, B.; Ladwig, K.-H.; Rein, T.; Gassen, N. C.; Binder, E. B.: Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-kappa B-driven inflammation and cardiovascular risk. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 116 (23), pp. 11370 - 11379 (2019)

Martinelli, S.; Wiechmann, T.; Kathrin, H.; Meinhold, L.; Roeh, S.; Sauer, S.; Gassen, N.; Binder, E. B.: Unravelling the differential role of FKBP51 (FK506 Binding Protein 5) isoforms in different cellular pathways. In European Neuropsychopharmacology, 29, pp. S652 - S653. ECNP Workshop on Early Career Scientists in Europe, Nice, FRANCE, March 07, 2019 - March 10, 2019. Elsevier, Amsterdam (2019)

Martinelli, S.: Effect of stress on protein homeostasis mediated by FKBP51 as a possible mechanism underlying stress-related disorders. Dissertation, Ludwig-Maximilians-Universität München, München (2019)