Publications of Theo Rein

Schaefers, C.; Schmeisser, W.; John, H.; Worek, F.; Rein, T.; Rothmiller, S.; Schmidt, A.: Effects of the nerve agent VX on hiPSC-derived motor neurons. ARCHIVES OF TOXICOLOGY (2024)

Spengler, D.; Rein, T.: Peripheral immune cell-derived matrix metalloprotease 8 (MMP8): brain trafficking promotes depression-like behavior. SIGNAL TRANSDUCTION AND TARGETED THERAPY 9 (1), 136 (2024)

Fries, G. R.; Saldana, V. A.; Finnstein, J.; Rein, T.: Molecular pathways of major depressive disorder converge on the synapse. MOLECULAR PSYCHIATRY 28 (1), pp. 284 - 297 (2023)

Schmeisser, W.; Siegert, M.; Thiermann, H.; Rein, T.; John, H.: Highly stable peptide adducts from hard keratins as biomarkers to verify local sulfur mustard exposure of hair by high-resolution mass spectrometry. ARCHIVES OF TOXICOLOGY (2022)

Budzinski, M. L.; Sokn, C.; Gobbini, R.; Ugo, B.; Antunica-Noguerol, M.; Senin, S.; Bajaj, T.; Gassen, N. C.; Rein, T.; Schmidt, M. V. et al.; Binder, E. B.; Arzt, E.; Liberman, A. C.: Tricyclic antidepressants target FKBP51 SUMOylation to restore glucocorticoid receptor activity. MOLECULAR PSYCHIATRY (2022)

Schaefers, C.; Rothmiller, S.; Thiermann, H.; Rein, T.; Schmidt, A.: The Efficiency of Direct Maturation: the Comparison of Two hiPSC Differentiation Approaches into Motor Neurons. STEM CELLS INTERNATIONAL 2022, 1320950 (2022)

Rein, T.: Harnessing autophagy to fight SARS-CoV-2: An update in view of recent drug development efforts. JOURNAL OF CELLULAR BIOCHEMISTRY, e12775 (2021)

Schmeisser, W.; Lueling, R.; Steinritz, D.; Thiermann, H.; Rein, T.; John, H.: Transthyretin as a target of alkylation and a potential biomarker for sulfur mustard poisoning: Electrophoretic and mass spectrometric identification and characterization. DRUG TESTING AND ANALYSIS (2021)

Herrmann, L.; Ebert, T.; Rosen, H.; Novak, B.; Philipsen, A.; Touma, C.; Schreckenbach, M.; Gassen, N. C.; Rein, T.; Schmidt, U.: Analysis of the cerebellar molecular stress response led to first evidence of a role for FKBP51 in brain FKBP52 expression in mice and humans. NEUROBIOLOGY OF STRESS 15, 100401 (2021)

Klionsky, D.; Abdel-Aziz, A.; Abdelfatah, S.; Rein, T.; Brand-Saberi, B.; Dong, X. C.; Kenchappa, C. S.; Li, Z.; Lin, Y.; Oshima, S. et al.; Rong, Y.; Sluimer, J. C.; Stallings, C. L.; Tong, C.-K.; 2285 other, a.: Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). AUTOPHAGY 17 (1), pp. 1 - 382 (2021)

Rein, T.: Peptidylprolylisomerases, Protein Folders, or Scaffolders? The Example of FKBP51 and FKBP52. BIOESSAYS 42 (7), 1900250 (2020)

Rein, T.: Post-translational modifications and stress adaptation: the paradigm of FKBP51. BIOCHEMICAL SOCIETY TRANSACTIONS 48, pp. 441 - 449 (2020)

Rein, T.; Fries, G. R.: Molecular Psychiatry: Trends and Study Examples. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 21 (2), 459 (2020)

Schmidt, U.; Rein, T.: Novel treatment targets for COVID-19: Contribution from molecular psychiatry. WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY 21 (7), pp. 572 - 575 (2020)

Gassen, N. C.; Niemeyer, D.; Muth, D.; Corman, V. M.; Martinelli, S.; Gassen, A.; Hafner, K.; Papies, J.; Moesbauer, K.; Zellner, A. et al.; Zannas, A. S.; Herrmann, A.; Holsboer, F.; Brack-Werner, R.; Boshart, M.; Mueller-Myhsok, B.; Drosten, C.; Mueller, M. A.; Rein, T.: SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection. NATURE COMMUNICATIONS 10, 5770 (2019)

Rein, T.: Is Autophagy Involved in the Diverse Effects of Antidepressants? CELLS 8 (1), 44 (2019)

Zannas, A. S.; Jia, M.; Hafner, K.; Baumert, J.; Wiechmann, T.; Pape, J. C.; Arloth, J.; Koedel, M.; Martinelli, S.; Roitman, M. et al.; Roeh, S.; Haehle, A.; Emeny, R. T.; Iurato, S.; Carrillo-Roa, T.; Lahti, J.; Raikkonen, K.; Eriksson, J. G.; Drake, A. J.; Waldenberger, M.; Wahl, S.; Kunze, S.; Lucae, S.; Bradley, B.; Gieger, C.; Hausch, F.; Smith, A. K.; Ressler, K. J.; Mueller-Myhsok, B.; Ladwig, K.-H.; Rein, T.; Gassen, N. C.; Binder, E. B.: Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-kappa B-driven inflammation and cardiovascular risk. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 116 (23), pp. 11370 - 11379 (2019)

Gassen, N. C.; Hartmann, J.; Zannas, A. S.; Kretzschmar, A.; Zschocke, J.; Maccarrone, G.; Hafner, K.; Zellner, A.; Kollmannsberger, L. K.; Wag, K. V. et al.; Mehta, D.; Kloiber, S.; Turck, C. W.; Lucae, S.; Chrousos, G. P.; Holsboer, F.; Binder, E. B.; Ising, M.; Schmidt, M. V.; Rein, T.: FKBP51 inhibits GSK3 beta and augments the effects of distinct psychotropic medications. MOLECULAR PSYCHIATRY 21 (2), pp. 277 - 289 (2016)

Zannas, A.; Jia, M.; Baumert, J.; Hafner, K.; Ködel, M.; Hähle, A.; Iurato, S.; Carrillo Roa, T.; Emeny, R.; Lathi, J. et al.; Raikkonen, K.; Eriksson, J.; Drake, A.; Waldenberger, M.; Wahl, S.; Kunze, S.; Lucae, S.; Bradley, B.; Gieger, C.; Hausch, F.; Smith, A.; Ressler, K.; Müller-Myhsok, B.; Ladwig, K.-H.; Rein, T.; Gassen, N.; Binder, E.: Aging- and Stress-Related Epigenetic Disinhibition of FKBP5 Contributes to NF-KB-Driven Inflammation and Cardiovascular Risk. 56th Annual Meeting of the American-College-of-Neuropsychopharmacology (ACNP), Palm Springs, CA, December 03, 2017 - December 07, 2017. NEUROPSYCHOPHARMACOLOGY 42 (Suppl. 1), T26, pp. S310 - S311 (2017)

Schaefers, C.; Strobelt, R.; Seeger, T.; Thiermann, H.; Rein, T.; Schmidt, A.: Development of a neuronal test model from induced pluripotent stem cells to study the effects of exposure to various warfare agents. In Naunyn-Schmiedebergs Archives of Pharmacology, 392, p. S63 - S63. 21st Annual Meeting of the German-Society-for-Experimental-and-Clinical-Pharmacology-and-Toxicology (DGPT) / 21st Annual Meeting of the Association-of-the-Clinical-Pharmacology-Germany (VKliPha), Stuttgart, GERMANY, February 25, 2019 - February 28, 2019. Springer-Verlag Heidelberg, Heidelberg (2019)