Publications of Nils C. Gassen
All genres
Journal Article (18)
2024
Journal Article
15 (1), 2635 (2024)
SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration. NATURE COMMUNICATIONS
Journal Article
121 (52), e2417728121 (2024)
SKA2 enhances stress- related glucocorticoid receptor signaling through FKBP4-FKBP5 interactions in neurons. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Journal Article
25 (22), 12318 (2024)
Differential Dynamics and Roles of FKBP51 Isoforms and Their Implications for Targeted Therapies. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Journal Article
17 (834), eadj6603 (2024)
Inhibiting Hippo pathway kinases releases WWC1 to promote AMPAR-dependent synaptic plasticity and long-term memory in mice. SCIENCE SIGNALING 2023
Journal Article
145 (4), pp. 439 - 459 (2023)
Associations of psychiatric disease and ageing with FKBP5 expression converge on superficial layer neurons of the neocortex. ACTA NEUROPATHOLOGICA 2022
Journal Article
Tricyclic antidepressants target FKBP51 SUMOylation to restore glucocorticoid receptor activity. MOLECULAR PSYCHIATRY (2022)
Journal Article
8 (10), eabi4797 (2022)
Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism. SCIENCE ADVANCES
Journal Article
41 (10), 111766 (2022)
Hippo-released WWC1 facilitates AMPA receptor regulatory complexes for hippocampal learning. CELL REPORTS 2021
Journal Article
The co-chaperone Fkbp5 shapes the acute stress response in the paraventricular nucleus of the hypothalamus of male mice. MOLECULAR PSYCHIATRY (2021)
Journal Article
13, 731603 (2021)
Myo-Inositol Levels in the Dorsal Hippocampus Serve as Glial Prognostic Marker of Mild Cognitive Impairment in Mice. FRONTIERS IN AGING NEUROSCIENCE
Journal Article
15, 100401 (2021)
Analysis of the cerebellar molecular stress response led to first evidence of a role for FKBP51 in brain FKBP52 expression in mice and humans. NEUROBIOLOGY OF STRESS
Journal Article
12 (1), 4643 (2021)
Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion. NATURE COMMUNICATIONS
Journal Article
479, pp. 91 - 106 (2021)
Brain Expression, Physiological Regulation and Role in Motivation and Associative Learning of Peroxisome Proliferator-activated Receptor y. NEUROSCIENCE
Journal Article
53 (2), pp. 390 - 401 (2021)
Loss of the psychiatric risk factor SLC6A15 is associated with increased metabolic functions in primary hippocampal neurons. EUROPEAN JOURNAL OF NEUROSCIENCE 2020
Journal Article
228 (2), e13345 (2020)
Blunted leptin sensitivity during hedonic overeating can be reinstated by activating galanin 2 receptors (Gal2R) in the lateral hypothalamus. ACTA PHYSIOLOGICA 2019
Journal Article
10, 5770 (2019)
SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection. NATURE COMMUNICATIONS
Journal Article
116 (23), pp. 11370 - 11379 (2019)
Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-kappa B-driven inflammation and cardiovascular risk. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2016
Journal Article
21 (2), pp. 277 - 289 (2016)
FKBP51 inhibits GSK3 beta and augments the effects of distinct psychotropic medications. MOLECULAR PSYCHIATRY Conference Paper (1)
2017
Conference Paper
42 (Suppl. 1), T26, pp. S310 - S311 (2017)
Aging- and Stress-Related Epigenetic Disinhibition of FKBP5 Contributes to NF-KB-Driven Inflammation and Cardiovascular Risk. 56th Annual Meeting of the American-College-of-Neuropsychopharmacology (ACNP), Palm Springs, CA, December 03, 2017 - December 07, 2017. NEUROPSYCHOPHARMACOLOGY Meeting Abstract (1)
2019
Meeting Abstract
29, pp. S652 - S653. ECNP Workshop on Early Career Scientists in Europe, Nice, FRANCE, March 07, 2019 - March 10, 2019. Elsevier, Amsterdam (2019)
Unravelling the differential role of FKBP51 (FK506 Binding Protein 5) isoforms in different cellular pathways. In European Neuropsychopharmacology,